Successful treatment of empyema thoracis with human recombinant deoxyribonuclease

Successful treatment of empyema thoracis with human recombinant deoxyribonuclease.

Fibrinolytic enzymes, particularly streptokinase, are now widely used to treat empyema thoracis. Recent in vitro evidence suggests that streptokinase has no effect on pus viscosity but that deoxyribonuclease (DNase) reduces the viscosity of pus. We report the first use of human recombinant DNase given intrapleurally to treat an empyema which had not resolved after standard treatment with strept...

Treatment of empyema thoracis.

Empyema Thoracis

Epmyema thoracis is associated with high mortality ranging between 6% to 24%. The incidence of empyema is increasing in both children and adults; the cause of this surge is unknown. Most cases of empyema complicate community- or hospital-acquired pneumonia but a proportion results from iatrogenic causes or develops without pneumonia. Parapneumonic effusions (PPE) develop in about one half of th...

[Treatment of empyema thoracis in children].

Empyema, an accumulation of infected fluid in the thoracic cavity, is commonly secondary to bacterial pneumonia in children. Despite the high prevalence and availability of many medical treatment options, there is no general consensus on the optimal management approach, which would lead to full and rapid recovery. Especially, there are the big differences in treatment options for the child with...

Treatment of Acute Empyema Thoracis with Intramuscular and Intrapleural

For chronic fissure in ano, surgical excision and suture has been practised with surprisingly good results. A stay suture is inserted at the proximal and distal extremities of the fissure which is made prominent by tension on each stay. The fissure is then easily excised with the subjacent portion of the subcutaneous external sphincter. Two or three figure-of-eight sutures of fine nylon are pla...